Steroids = weaksauce

**el_jefe** · 03-28-2008, 01:13 PM

Myostatin inhibitor trials on humans

As noted by the facioscapulohumeral muscular dystrophy (FSHD) society, myostatin inhibitor clinical trials have begun on humans. The first trials on humans actually started in Feb, 2005.

This is related to my article which indicated that testing on mice indicated that myostatin drugs had four times the muscle growth effect as high doses of steroids but with less side effects.

these are pictures of a German boy that naturally has the genes for inhibiting myostatin

There was also the discovery of a superstrong american boy who also has the natural genes for hypermuscles.

"He could do the iron cross when he was 5 months old," said his adoptive mother, Dana Hoekstra of Roosevelt Park. She was referring to a difficult gymnastics move in which a male athlete suspends himself by his arms between two hanging rings, forming the shape of a cross.

Liam has the kind of physical attributes that bodybuilders and other athletes dream about: 40 percent more muscle mass than normal, jaw-dropping strength, breathtaking quickness, a speedy metabolism and almost no body fat.

Liam can run like the wind, has the agility of a cat, lifts pieces of furniture that most children his age couldn't push across a slick floor and eats like there is no tomorrow -- without gaining weight.

Liam Hoekstra was hanging upside down by his feet when he performed an inverted sit-up, his shirt falling away to expose rippled abdominal muscles. It was a display of raw power one might expect to see from an Olympic gymnast. Liam is 19 months old.

The so-called myostatin blockade has generated tremendous interest in the bodybuilding community. Some [COLOR=blue ! important][COLOR=blue ! important]nutritional [COLOR=blue ! important]supplements[/color][/color][/color] claim to block myostatin, but researchers have said the claims are not scientifically valid.

"If the myostatin protein is knocked out, muscles grow and rejuvenate much more quickly," Dr. Larson said. "It has potential for great abuse in the future as the new steroid."

[Despite being born to a troubled mother who gave him up for adoption at birth and Liam being born with a suite of medical problems not related to the muscle genes.] Liam being born four weeks early and had a small hole in his heart. He also had eczema, enlarged kidneys, was lactose intolerant and had severe stomach reflux that made him vomit several times each day, his mother said. Two days after he was born, Liam could stand up and support his weight if someone held his hands to provide balance.

His is one of roughly 100 known cases in the world, according to experts and medical literature.

**CHAOS** · 03-28-2008, 01:18 PM

wow thats pretty wild about the kid

**SmervE AttacK** · 03-28-2008, 01:30 PM

what a lucky sob.

**kenskiv** · 03-28-2008, 01:54 PM

Quote:

Originally Posted by SwervE

what a lucky sob.

Yeah those first years were rough...Glad i'm all grown up now

**myfault** · 03-28-2008, 05:19 PM

i would like to inhibit the myostatin in my penis please.

**Vissionary** · 03-28-2008, 05:22 PM

^seconded

**el_jefe** · 03-28-2008, 05:50 PM

You guys didn't click the link, did you?

**el_jefe** · 03-28-2008, 05:52 PM

Quote:

The clinical study details

Each site will enroll 12 patients. 4 FSHD, 4 LGMD, 4 Becker MD.

Initial toxicity studies are done. There some side effects that are consistent with monoclonal antibody therapy.

This next stage of the trial is to determine dosing at three different levels and clinical efficacy.

Patients must be genetically confirmed.

The MSTN-inhibitor drug is administered via intravenous infusion.

Initial patient visit/transfusion may or may nor require an overnight stay. New infusion every other week for six months and three more months follow-up. Two muscle biopsies are optional.

Patients should have average [COLOR=blue ! important][COLOR=blue ! important]muscle [COLOR=blue ! important]strength[/color][/color][/color] grade of 3. As general rule patient should be able to walk 30 feet unaided except for use of orthotic braces e.g. AFOs.

Phase I and phase II clinical trials are under way.

In Phase I clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.

In Phase II clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.

In Phase III studies, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.

In other words, you will be able to juice up with inhibitors

**Alec Trevelyan** · 03-31-2008, 07:14 PM

Theres a HUGE thread about this topic on BB.com! Looks to be pretty intersting but they need more research done on it.

http://forum.bodybuilding.com/showthread.php?t=720382

03-28-2008, 01:13 PM	#1 (permalink)
el_jefe SOT Post Whore Join Date: Jun 2006 Location: BFE Arizona Posts: 12,094 gXboxLive Leaderboard: 20^th	Steroids = weaksauce Myostatin inhibitor trials on humans As noted by the facioscapulohumeral muscular dystrophy (FSHD) society, myostatin inhibitor clinical trials have begun on humans. The first trials on humans actually started in Feb, 2005. This is related to my article which indicated that testing on mice indicated that myostatin drugs had four times the muscle growth effect as high doses of steroids but with less side effects. these are pictures of a German boy that naturally has the genes for inhibiting myostatin There was also the discovery of a superstrong american boy who also has the natural genes for hypermuscles. "He could do the iron cross when he was 5 months old," said his adoptive mother, Dana Hoekstra of Roosevelt Park. She was referring to a difficult gymnastics move in which a male athlete suspends himself by his arms between two hanging rings, forming the shape of a cross. Liam has the kind of physical attributes that bodybuilders and other athletes dream about: 40 percent more muscle mass than normal, jaw-dropping strength, breathtaking quickness, a speedy metabolism and almost no body fat. Liam can run like the wind, has the agility of a cat, lifts pieces of furniture that most children his age couldn't push across a slick floor and eats like there is no tomorrow -- without gaining weight. Liam Hoekstra was hanging upside down by his feet when he performed an inverted sit-up, his shirt falling away to expose rippled abdominal muscles. It was a display of raw power one might expect to see from an Olympic gymnast. Liam is 19 months old. The so-called myostatin blockade has generated tremendous interest in the bodybuilding community. Some [COLOR=blue ! important][COLOR=blue ! important]nutritional [COLOR=blue ! important]supplements[/color][/color][/color] claim to block myostatin, but researchers have said the claims are not scientifically valid. "If the myostatin protein is knocked out, muscles grow and rejuvenate much more quickly," Dr. Larson said. "It has potential for great abuse in the future as the new steroid." [Despite being born to a troubled mother who gave him up for adoption at birth and Liam being born with a suite of medical problems not related to the muscle genes.] Liam being born four weeks early and had a small hole in his heart. He also had eczema, enlarged kidneys, was lactose intolerant and had severe stomach reflux that made him vomit several times each day, his mother said. Two days after he was born, Liam could stand up and support his weight if someone held his hands to provide balance. His is one of roughly 100 known cases in the world, according to experts and medical literature. __________________

03-28-2008, 01:18 PM	#2 (permalink)
CHAOS SOT Screwdriver Goes Where Mod Join Date: Jul 2007 Location: Fucking Bullshit. Posts: 20,254 gXboxLive Leaderboard: 44^th	wow thats pretty wild about the kid __________________ SOT - you aint... no goon.

03-28-2008, 01:30 PM	#3 (permalink)
SmervE AttacK Truck Stop Bathroom MOD Join Date: Jun 2006 Location: central PA Posts: 15,866 gXboxLive Leaderboard: 25^th	what a lucky sob. __________________

03-28-2008, 05:22 PM	#6 (permalink)
Vissionary SOT Super Moderator Join Date: Jun 2006 Location: SoCal Posts: 45,210 gXboxLive Leaderboard: 43^rd	^seconded __________________ SOT - We'll pull your endocrine system out of your body and make a hat out of it.

03-28-2008, 05:50 PM	#7 (permalink)
el_jefe SOT Post Whore Join Date: Jun 2006 Location: BFE Arizona Posts: 12,094 gXboxLive Leaderboard: 20^th	You guys didn't click the link, did you? __________________

03-28-2008, 05:19 PM	#5 (permalink)
myfault SOT Member Join Date: Jun 2006 Posts: 1,123	i would like to inhibit the myostatin in my penis please.

03-31-2008, 07:14 PM	#9 (permalink)
Alec Trevelyan SOT Senior Member Join Date: May 2006 Posts: 1,914	Theres a HUGE thread about this topic on BB.com! Looks to be pretty intersting but they need more research done on it. http://forum.bodybuilding.com/showthread.php?t=720382 __________________ .....Revenge is good!!! Venegeful is great!

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